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Modelling Uptake Sensitivities of Connected and Automated Vehicle Technologies
Connected and automated vehicle (CAV) technologies and services are rapidly developing and have the potential to revolutionise the transport systems. However, like many innovations, the uptake pathways are uncertain. The focus...
Published by: IGI Global
Modelling the Impacts of Inter-City Connectivity on City Specialisation
There is a high level of interest in investing in inter-city connectivity schemes. The rationale for these schemes is improved economic performance through increased productivity, jobs, and output. The mobility costs of...
Published by: IGI Global
Digital Leadership
Simon Hensellek
Jan 01, 2020
Advances in digitalization place completely new demands on both political and economic leaders as well as on society as a whole. In addition to technical skills as a basis for dealing with and understanding digital technologies...
Published by: IGI Global
Photoplethysmography Heart Rate Monitoring
Research conducted by the World Health Organisation (WHO) in 2018 demonstrated that the worldwide threat of cardiovascular diseases (CVDs) has increased compared to previous years. CVDs are very dangerous: if timely treatment is...
Published by: IGI Global
COVIDiots and Cogency
The COVID-19 pandemic in the United States spawns a perplexing polemic. Intransigent coronavirus skeptics who defy public health recommendations often get cast as ideological zealots or as perniciously ignorant. Both...
Published by: IGI Global
Tools for Sustainable Change
This research focuses on the ability of spatial decision-support tools (SDST) to transform urban regeneration processes through collaborative planning between authorities and communities. This article presents what was learned...
Published by: IGI Global
Investigating Student Perceptions and the Effectiveness of K-12 Blended Learning Communities
Richard Hartshorne, Gina Tovine, April Fleetwood, Andrew Shepherd, Colton Tapoler, Raquel Pesce
Jan 11, 2019
While the growth of blended learning environments in higher education and non-educational settings has continued to increase in recent years, this has not been the case in K-12 settings. Recently, in an effort to explore the...
Published by: IGI Global
Investigating Student Perceptions and the Effectiveness of K-12 Blended Learning Communities
Richard Hartshorne, Gina Tovine, April Fleetwood, Andrew Shepherd, Colton Tapoler, Raquel Pesce
Sep 02, 2022
While the growth of blended learning environments in higher education and non-educational settings has continued to increase in recent years, this has not been the case in K-12 settings. Recently, in an effort to explore the...
Web-Based Teaching & Learning Education Curriculum Development and Instructional Design Computer Science and Information Technology Media and Communications
Published by: IGI Global
Participation in Software Development
Francis Harvey, Aura Moldovan, Eric Losang, Tim Leibert, Maria Turchenko, Nicola Simon, Rowenia Bender
Jan 01, 2022
Participatory planning holds important lessons for improving local government capabilities and responsiveness, but overall procedural regulations and statutory frameworks make its relevance for participatory IT development often...
Published by: IGI Global
Regulation of immune responses in primary biliary cholangitis
Victoria Mulcahy, Evaggelia Liaskou, Jose-Ezequiel Martin, Prasanti Kotagiri, Jonathan Badrock, Rebecca L Jones, Simon M Rushbrook, Stephen D Ryder, Douglas Thorburn, Simon D Taylor-Robinson, Graeme Clark, Heather J Cordell, Richard N Sandford, David E Jones, Gideon M Hirschfield, George F Mells
Apr 17, 2023
BACKGROUND AIMS: In patients with primary biliary cholangitis (PBC), the serum liver biochemistry measured during treatment with ursodeoxycholic acid-the UDCA response-accurately predicts long-term outcome. Molecular...
Kinova Modular Robot Arms for Service Robotics Applications
Alexandre Campeau-Lecours, Hugo Lamontagne, Simon Latour, Philippe Fauteux, Véronique Maheu, François Boucher, Charles Deguire, Louis-Joseph L'Ecuyer
Jul 01, 2017
This article presents Kinova's modular robotic systems, including the robots JACO2 and MICO2, actuators and grippers. Kinova designs and manufactures robotics platforms and components that are simple, sexy and safe under two...
Published by: IGI Global
Stable endocytic structures navigate the complex pellicle of apicomplexan parasites
Ludek Koreny, Brandon N Mercado-Saavedra, Christen M Klinger, Konstantin Barylyuk, Simon Butterworth, Jennifer Hirst, Yolanda Rivera-Cuevas, Nathan R Zaccai, Victoria JC Holzer, Andreas Klingl, Joel B Dacks, Vern B Carruthers, Margaret S Robinson, Simon Gras, Ross F Waller
Apr 15, 2023
The evolution of the Galápagos mantle plume.
Caroline R Soderman, Oliver Shorttle, Esteban Gazel, Dennis J Geist, Simon Matthews, Helen M Williams
Apr 09, 2023
The lavas associated with mantle plumes may sample domains throughout Earth's mantle and probe its dynamics. However, plume studies are often only able to take snapshots in time, usually of the most recent plume activity...
Maternal immunisation against Group B Streptococcus
Simon R Procter, Bronner P Gonçalves, Proma Paul, Jaya Chandna, Farah Seedat, Artemis Koukounari, Raymond Hutubessy, Caroline Trotter, Joy E Lawn, Mark Jit
Apr 14, 2023
Background
Group B Streptococcus (GBS) can cause invasive disease (iGBS) in young infants, typically presenting as sepsis or meningitis, and is also associated with stillbirth and preterm birth. GBS vaccines are under...
Humans Streptococcus Agalactiae Streptococcal Infections premature birth vaccines Immunization Vaccination Bayes Theorem Pregnancy Quality of life Infant Infant Newborn Cost-Benefit Analysis Female Stillbirth
Published by: PLoS Medicine
Large scale crowdsourced radiotherapy segmentations across a variety of cancer anatomic sites.
Kareem A Wahid, Diana Lin, Onur Sahin, Michael Cislo, Benjamin E Nelms, Renjie He, Mohammed A Naser, Simon Duke, Michael V Sherer, John P Christodouleas, Abdallah S R Mohamed, James D Murphy, Clifton D Fuller, Erin F Gillespie
Apr 17, 2023
Clinician generated segmentation of tumor and healthy tissue regions of interest (ROIs) on medical images is crucial for radiotherapy. However, interobserver segmentation variability has long been considered a significant...
Humans Neoplasms Tomography X-Ray Computed Radiotherapy Planning Computer-Assisted Radiation Oncology Image Processing Computer-Assisted Female Crowdsourcing
Published by: Scientific data
Research priorities relating to the delivery of cardiovascular prevention and rehabilitation programmes
Sheona McHale, Aynsley Cowie, Sarah Brown, Tom Butler, Kathryn Carver, Hasnain M Dalal, Susan Dawkes, Carolyn Deighan, Patrick Doherty, Jo Evans, Sally Hinton, Jennifer Jones, Joseph Mills, Simon Nichols, Rod S Taylor
Apr 17, 2023
OBJECTIVE: The purpose of this British Association for Cardiovascular Prevention and Rehabilitation (BACPR) research priority setting project (PSP) was to identify a top 10 list of priority research questions for cardiovascular...
Antigen discrimination by T cells relies on size-constrained microvillar contact.
Edward Jenkins, Markus Körbel, Caitlin O'Brien-Ball, James McColl, Kevin Y Chen, Mateusz Kotowski, Jane Humphrey, Anna H Lippert, Heather Brouwer, Ana Mafalda Santos, Steven F Lee, Simon J Davis, David Klenerman
Apr 17, 2023
T cells use finger-like protrusions called 'microvilli' to interrogate their targets, but why they do so is unknown. To form contacts, T cells must overcome the highly charged, barrier-like layer of large molecules forming a...
T-Lymphocytes microvilli Receptors Antigen T-Cell Antigens Lymphocyte Activation Signal Transduction
Published by: Nature Communications
A rare human variant that disrupts GPR10 signalling causes weight gain in mice.
Fleur Talbot, Claire H Feetham, Jacek Mokrosiński, Katherine Lawler, Julia M Keogh, Elana Henning, Edson Mendes de Oliveira, Vikram Ayinampudi, Sadia Saeed, Amélie Bonnefond, Mohammed Arslan, Giles S H Yeo, Philippe Froguel, David A Bechtold, Antony Adamson, Neil Humphreys, Inês Barroso, Simon M Luckman, I Sadaf Farooqi
Apr 15, 2023
Animals Mice Transgenic Humans Mice obesity Weight Gain Receptors G-Protein-Coupled Signal Transduction Energy Metabolism
Published by: Nature Communications
The SARS-CoV-2 Alpha variant was associated with increased clinical severity of COVID-19 in Scotland
David J. Pascall, Elen Vink, Rachel Blacow, Naomi Bulteel, Alasdair Campbell, Robyn Campbell, Sarah Clifford, Chris Davis, Ana da Silva Filipe, Noha El Sakka, Ludmila Fjodorova, Ruth Forrest, Emily Goldstein, Rory Gunson, John Haughney, Matthew T. G. Holden, Patrick Honour, Joseph Hughes, Edward James, Tim Lewis, Samantha Lycett, Oscar MacLean, Martin McHugh, Guy Mollett, Yusuke Onishi, Ben Parcell, Surajit Ray, David L. Robertson, Sharif Shabaan, James G. Shepherd, Katherine Smollett, Kate Templeton, Elizabeth Wastnedge, Craig Wilkie, Thomas Williams, Emma C. Thomson, The COVID-19 Genomics UK (COG-UK) Consortium
Apr 13, 2023
RESEARCH ARTICLE People and places Physical sciences Biology and life sciences Medicine and Health Sciences Computer and information sciences
Published by: Public Library of Science
Psychometric properties of an innovative smartphone application to investigate the daily impact of hypoglycemia in people with type 1 or type 2 diabetes
Uffe Søholm, Melanie Broadley, Natalie Zaremba, Patrick Divilly, Giesje Nefs, Jill Carlton, Julia K Mader, Petra Martina Baumann, Mikel Gomes, Gilberte Martine-Edith, Daniel J Pollard, Dajana Rath, Simon Heller, Ulrik Pedersen-Bjergaard, Rory J McCrimmon, Eric Renard, Mark Evans, Bastiaan de Galan, Thomas Forkmann, Stephanie A Amiel, Christel Hendrieckx, Jane Speight, Pratik Choudhary, Frans Pouwer
Apr 17, 2023
Introduction
The aim of this study was to determine the acceptability and psychometric properties of the Hypo-METRICS (Hypoglycemia MEasurement, ThResholds and ImpaCtS) application (app): a novel tool designed to assess...
Humans Diabetes mellitus Type 1 Diabetes mellitus Type 2 Hypoglycemia Insulin Reproducibility of Results Psychometrics Adult Aged Middle Aged Benchmarking Mobile Applications Smartphone Surveys and Questionnaires
Published by: PLOS ONE
Assessment of association between lower ureteric excision technique and oncological outcomes for upper urinary tract urothelial carcinoma
James Peter Blackmur, Etienne Chew, Matthew Trail, Katie Brodie, Nicola Santoni, Flora Rodger, David Hamilton, Fortis Gaba, Sophie Randall, Sarika Nalagatla, Brian Little, Khalid Janjua, Clare Sweeney, Andrew Martindale, Khaver Qureshi, Antony Riddick, Kevin O'Connor, S Alan McNeill, Simon Phipps, Mark L Cutress, Edward AA Mains, Ian Dunn, Sarah Reid, Grant D Stewart, Gavin Lamb, Muhammad Zeeshan Aslam, Steve Leung, Ross Clark, Ian Wilson, Grenville Oades, Alexander Chapman, Alexander Laird
Apr 08, 2023
Genetic forms of primary progressive aphasia within the GENetic Frontotemporal dementia Initiative (GENFI) cohort
Kiran Samra, Amy M MacDougall, Arabella Bouzigues, Martina Bocchetta, David M Cash, Caroline V Greaves, Rhian S Convery, Chris Hardy, John C van Swieten, Harro Seelaar, Lize C Jiskoot, Fermin Moreno, Raquel Sanchez-Valle, Robert Laforce, Caroline Graff, Mario Masellis, Maria Carmela Tartaglia, James B Rowe, Barbara Borroni, Elizabeth Finger, Matthis Synofzik, Daniela Galimberti, Rik Vandenberghe, Alexandre de Mendonça, Chris R Butler, Alexander Gerhard, Simon Ducharme, Isabelle Le Ber, Isabel Santana, Florence Pasquier, Johannes Levin, Markus Otto, Sandro Sorbi, Jason D Warren, Jonathan D Rohrer, Lucy L Russell, Genetic Frontotemporal dementia Initiative (GENFI)
Apr 17, 2023
Structural MRI predicts clinical progression in presymptomatic genetic frontotemporal dementia
Martina Bocchetta, Emily G Todd, Arabella Bouzigues, David M Cash, Jennifer M Nicholas, Rhian S Convery, Lucy L Russell, David L Thomas, Ian B Malone, Juan Eugenio Iglesias, John C van Swieten, Lize C Jiskoot, Harro Seelaar, Barbara Borroni, Daniela Galimberti, Raquel Sanchez-Valle, Robert Laforce, Fermin Moreno, Matthis Synofzik, Caroline Graff, Mario Masellis, Maria Carmela Tartaglia, James B Rowe, Rik Vandenberghe, Elizabeth Finger, Fabrizio Tagliavini, Alexandre de Mendonça, Isabel Santana, Chris R Butler, Simon Ducharme, Alexander Gerhard, Adrian Danek, Johannes Levin, Markus Otto, Sandro Sorbi, Isabelle Le Ber, Florence Pasquier, Jonathan D Rohrer, Genetic Frontotemporal dementia Initiative (GENFI)
Apr 17, 2023
p53 and ovarian carcinoma survival
Martin Köbel, Eun-Young Kang, Ashley Weir, Peter F Rambau, Cheng-Han Lee, Gregg S Nelson, Prafull Ghatage, Nicola S Meagher, Marjorie J Riggan, Jennifer Alsop, Michael S Anglesio, Matthias W Beckmann, Christiani Bisinotto, Michelle Boisen, Jessica Boros, Alison H Brand, Angela Brooks-Wilson, Michael E Carney, Penny Coulson, Madeleine Courtney-Brooks, Kara L Cushing-Haugen, Cezary Cybulski, Suha Deen, Mona A El-Bahrawy, Esther Elishaev, Ramona Erber, Sian Fereday, Anna Fischer, Simon A Gayther, Arantzazu Barquin-Garcia, Aleksandra Gentry-Maharaj, C Blake Gilks, Helena Gronwald, Marcel Grube, Paul R Harnett, Holly R Harris, Andreas D Hartkopf, Arndt Hartmann, Alexander Hein, Joy Hendley, Brenda Y Hernandez, Yajue Huang, Anna Jakubowska, Mercedes Jimenez-Linan, Michael E Jones, Catherine J Kennedy, Tomasz Kluz, Jennifer M Koziak, Jaime Lesnock, Jenny Lester, Jan Lubiński, Teri A Longacre, Maria Lycke, Constantina Mateoiu, Bryan M McCauley, Valerie McGuire, Britta Ney, Alexander Olawaiye, Sandra Orsulic, Ana Osorio, Luis Paz-Ares, Teresa Ramón Y Cajal, Joseph H Rothstein, Matthias Ruebner, Minouk J Schoemaker, Mitul Shah, Raghwa Sharma, Mark E Sherman, Yurii B Shvetsov, Naveena Singh, Helen Steed, Sarah J Storr, Aline Talhouk, Nadia Traficante, Chen Wang, Alice S Whittemore, Martin Widschwendter, Lynne R Wilkens, Stacey J Winham, Javier Benitez, Andrew Berchuck, David D Bowtell, Francisco J Candido Dos Reis, Ian Campbell, Linda S Cook, Anna DeFazio, Jennifer A Doherty, Peter A Fasching, Renée T Fortner, María J García, Marc T Goodman, Ellen L Goode, Jacek Gronwald, David G Huntsman, Beth Y Karlan, Linda E Kelemen, Stefan Kommoss, Nhu D Le, Stewart G Martin, Usha Menon, Francesmary Modugno, Paul DP Pharoah, Joellen M Schildkraut, Weiva Sieh, Annette Staebler, Karin Sundfeldt, Anthony J Swerdlow, Susan J Ramus, James D Brenton
Apr 17, 2023
p53 ovarian cancer Prognosis Clear cell TP53 High-grade Serous Carcinoma Endometrioid Humans Carcinoma Endometrioid Ovarian Neoplasms Female Tumor Suppressor Protein p53 Carcinoma Ovarian Epithelial
Published by: The journal of pathology. Clinical research
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